Assessment of salivary antibody response to BNT162b2 mRNA COVID‐19 vaccination

Abstract

Journal of Medical VirologyVolume 93, Issue 9 p. 5257-5259 LETTER TO THE EDITOR Assessment of salivary antibody response to BNT162b2 mRNA COVID-19 vaccination Ivana Lapić, Corresponding Author Ivana Lapić [email protected] Department of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, Croatia Correspondence Ivana Lapić, Department of Laboratory Diagnostics, University Hospital Center Zagreb, Kišpatićeva 12, 10 000 Zagreb, Croatia. Email: [email protected]Search for more papers by this authorDragana Šegulja, Dragana Šegulja Department of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, CroatiaSearch for more papers by this authorDunja Rogić, Dunja Rogić Department of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, CroatiaSearch for more papers by this author Ivana Lapić, Corresponding Author Ivana Lapić [email protected] Department of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, Croatia Correspondence Ivana Lapić, Department of Laboratory Diagnostics, University Hospital Center Zagreb, Kišpatićeva 12, 10 000 Zagreb, Croatia. Email: [email protected]Search for more papers by this authorDragana Šegulja, Dragana Šegulja Department of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, CroatiaSearch for more papers by this authorDunja Rogić, Dunja Rogić Department of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, CroatiaSearch for more papers by this author First published: 19 May 2021 https://doi.org/10.1002/jmv.27096Citations: 16Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechat No abstract is available for this article. REFERENCES 1 Lippi G, Sciacovelli L, Trenti T, Plebani M, Executive Board of SIBioC (Società Italiana di Biochimica Clinica e Biologia Molecolare Clinica). Kinetics and biological characteristics of humoral response developing after SARS-CoV-2 infection: implications for vaccination [published online ahead of print January 21, 2021]. Clin Chem Lab Med. https://doi.org/10.1515/cclm-2021-0038 10.1515/cclm-2021-0038 Web of Science®Google Scholar 2 Danese E, Montagnana M, Salvagno GL, et al. Comprehensive assessment of humoral response after Pfizer BNT162b2 mRNA Covid-19 vaccination: a three-case series [published online ahead of print April 12, 2021]. Clin Chem Lab Med. https://doi.org/10.1515/cclm-2021-0339 10.1515/cclm-2021-0339 Web of Science®Google Scholar 3 Mulligan MJ, Lyke KE, Kitchin N, et al. Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults. Nature. 2020; 586: 589-593. 10.1038/s41586-020-2639-4 CASPubMedWeb of Science®Google Scholar 4 Padoan A, Dall'Olmo L, Rocca FD, et al. Antibody response to first and second dose of BNT162b2 in a cohort of characterized healthcare workers. Clin Chim Acta. 2021; 519: 60-63. 10.1016/j.cca.2021.04.006 CASPubMedWeb of Science®Google Scholar 5 Aita A, Basso D, Cattelan AM, et al. SARS-CoV-2 identification and IgA antibodies in saliva: one sample two tests approach for diagnosis. Clin Chim Acta. 2020; 510: 717-722. 10.1016/j.cca.2020.09.018 CASPubMedWeb of Science®Google Scholar 6 Isho B, Abe KT, Zuo M, et al. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Sci Immunol. 2020; 5:eabe5511. 10.1126/sciimmunol.abe5511 PubMedWeb of Science®Google Scholar 7 Pisanic N, Randad PR, Kruczynski K, et al. COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva. J Clin Microbiol. 2020; 59:e02204. 10.1128/JCM.02204-20 PubMedWeb of Science®Google Scholar 8 Roche Diagnostics. Elecsys Anti-SARS-CoV-2 S [package insert]V2.0. Google Scholar 9 Jafarzadeh A, Sadeghi M, Karam GA, Vazirinejad R. Salivary IgA and IgE levels in healthy subjects: relation to age and gender. Braz Oral Res. 2010; 24: 21-27. 10.1590/S1806-83242010000100004 PubMedGoogle Scholar 10 Ketas TJ, Chaturbhuj D, Cruz-Portillo VM, et al. Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva. bioRxiv. 2021 PubMedGoogle Scholar 11 Becker M, Dulovic A, Junker D, et al. Immune response to SARS-CoV-2 variants of concern in vaccinated individuals. medRxiv. 2021. Google Scholar Citing Literature Volume93, Issue9Special Issue on New coronavirus (2019‐nCoV or SARS‐CoV‐2) and the outbreak of the respiratory illness (COVID‐19): Part‐XIVSeptember 2021Pages 5257-5259 ReferencesRelatedInformation

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