<i>Exo</i>-Selective and Enantioselective Photoenolization/Diels–Alder Reaction
Min Hou, Mengmeng Xu, Baochao Yang, Haibing He, Shuanhu Gao
Abstract
-selective photoenolization/Diels-Alder reaction of electron-rich 2-methylbenzaldehydes and dienophiles containing a benzoyl group at its α position was reported herein. The chiral TADDOL-type ligand plays a key role in this process: (1) accelerating the reaction; (2) controlling the enantioselectivity; and (3) improving and tuning the diastereoselectivity of the reaction.
Topics & Concepts
ChemistryDiels–Alder reactionEnantioselective synthesisLigand (biochemistry)Combinatorial chemistryOrganic chemistryCatalysisReceptorBiochemistryRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods