Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model
Zain Zaki Zakaria, Nouf N. Mahmoud, Fatiha M. Benslimane, Huseyin C. Yalcin, Ala‐Eddin Al Moustafa, Maha Al‐Asmakh
Abstract
BACKGROUND: ) early life stages. METHODS: in this study, zebrafish embryos were exposed to surface-modified AuNRs at concentrations ranging from 1 to 20 μg/mL. Lethality and developmental endpoints such as hatching, tail flicking, and developmental delays were assessed until 96 h post-fertilization (hpf). RESULTS: . CONCLUSIONS: pathways as a suggested mechanism of action and toxicity modality.
Topics & Concepts
ZebrafishNanorodToxicityNanotechnologyChemistryMaterials scienceBiochemistryGeneOrganic chemistryNanoparticles: synthesis and applicationsGold and Silver Nanoparticles Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniques