Deoxycholic Acid Promotes Pyroptosis in Free Fatty Acid-Induced Steatotic Hepatocytes by Inhibiting PINK1-Mediated Mitophagy
Xuebin Gao, Yongdui Ruan, Xuan Zhu, Xiaozhuan Lin, Xin Yan, Xiang Li, Meiqing Mai, Honghui Guo
Topics & Concepts
PyroptosisMitophagyNonalcoholic fatty liver diseaseInflammasomeChemistryDeoxycholic acidSteatosisPINK1Liver injuryFatty liverBiochemistryPharmacologyCell biologyBile acidBiologyInternal medicineEndocrinologyMedicineAutophagyApoptosisDiseaseReceptorLiver Disease Diagnosis and TreatmentInflammasome and immune disordersAutophagy in Disease and Therapy