The emerging role of skeletal muscle as a modulator of lipid profile the role of exercise and nutrition
Tzortzis Nomikos, Spyridon Methenitis, Demosthenes B. Panagiotakos
Abstract
The present article aims to discuss the hypothesis that skeletal muscle per se but mostly its muscle fiber composition could be significant determinants of lipid metabolism and that certain exercise modalities may improve metabolic dyslipidemia by favorably affecting skeletal muscle mass, fiber composition and functionality. It discusses the mediating role of nutrition, highlights the lack of knowledge on mechanistic aspects of this relationship and proposes possible experimental directions in this field.
Topics & Concepts
Skeletal muscleLipidologyDyslipidemiaClinical nutritionClinical chemistryLipid metabolismSports nutritionModalitiesMedicineBiologyInternal medicineEndocrinologyBioinformaticsAthletesPhysical therapyObesitySocial scienceSociologyAdipose Tissue and MetabolismMuscle metabolism and nutritionDiet and metabolism studies