Alkaloid-rich fraction of Ervatamia coronaria sensitizes colorectal cancer through modulating AMPK and mTOR signalling pathways
Naibedya Dutta, Deepak B. Pemmaraju, Suvranil Ghosh, Asif Ali, Ayan Mondal, Chirantan Majumder, Vinod Kumar Nelson, Subhash C. Mandal, Anup Kumar Misra, Aravind Kumar Rengan, Velyutham Ravichandiran, Chun‐Tao Che, Katerina V. Gurova, Andrei V. Gudkov, Mahadeb Pal
Topics & Concepts
PI3K/AKT/mTOR pathwayAMPKProtein kinase BCancer researchAutophagyCell cycleCell cycle checkpointMAPK/ERK pathwayP70-S6 Kinase 1Cyclin-dependent kinaseCell growthChemistryPharmacologyApoptosisMedicineKinaseBiologyCell biologyProtein kinase ABiochemistryPI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and CancerCancer-related Molecular Pathways