Multi-targeted anti-Alzheimer's agents: Synthesis, biological evaluation, and molecular modeling study of some pyrazolopyridine hybrids
Omnia M. Waly, Selwan M. El‐Sayed, Mariam A. Ghaly, Hussein I. El‐Subbagh
Topics & Concepts
ChemistryLipinski's rule of fiveIC50NeurotoxicityRivastigminePharmacologyStereochemistryLead compoundCombinatorial chemistryBiochemistryIn vitroToxicityOrganic chemistryDementiaDiseaseDonepezilGeneIn silicoPathologyMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsAlzheimer's disease research and treatments