Fucoxanthin regulates Nrf2 signaling to decrease oxidative stress and improves renal fibrosis depending on Sirt1 in HG-induced GMCs and STZ-induced diabetic rats
Guanyu Yang, Qingde Li, Jing Peng, Lin Jin, Xiaoyu Zhu, Dongxiao Zheng, Yingxia Zhang, Rong Wang, Yanting Song, Wenting Hu, Xi Xie
Topics & Concepts
FucoxanthinOxidative stressDiabetic nephropathyPharmacologySuperoxide dismutaseKidneyEndocrinologyChemistryKEAP1Internal medicineBiochemistryMedicineCarotenoidTranscription factorGeneGenomics, phytochemicals, and oxidative stressPregnancy and preeclampsia studiesBirth, Development, and Health