Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-β/ Smad4 axis driving the cells towards lethal EMT
Mir Mohd Faheem, Reyaz ur Rasool, Syed Mudabir Ahmad, Vijay Lakshmi Jamwal, Souneek Chakraborty, Archana Katoch, Sumit G. Gandhi, Madhulika Bhagat, Anindya Goswami
Topics & Concepts
Cancer researchSMADTransforming growth factorPancreatic cancerBiologyApoptosisCell biologyEctopic expressionCell cultureCancerGeneticsTGF-β signaling in diseasesPancreatic and Hepatic Oncology ResearchRenal and related cancers