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S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis

Liwen Deng, Flavia G. Costa, Kimbria J. Blake, Samantha Choi, Arundhasa Chandrabalan, Muhammad Saad Yousuf, Stephanie Shiers, D Dubreuil, Daniela Vega‐Mendoza, Corinne Rolland, Céline Deraison, Tiphaine Voisin, Michelle D. Bagood, Lucia Wesemann, Abigail M Frey, Joseph S. Palumbo, Brian J. Wainger, Richard L. Gallo, Juan Manuel Leyva-Castillo, Nathalie Vergnolle, Theodore J. Price, Rithwik Ramachandran, Alexander R. Horswill, Isaac M. Chiu

2023Cell144 citationsDOIOpen Access PDF

Topics & Concepts

BiologyStaphylococcus aureusGene knockdownProteaseSmall interfering RNAMicrobiologyMediatorProteasesScratchingSensory systemSkin infectionVirulence factorVirulenceImmunologyCell biologyRNABacteriaGeneGeneticsNeuroscienceEnzymeBiochemistryAcousticsPhysicsDermatology and Skin DiseasesToxin Mechanisms and ImmunotoxinsFood Allergy and Anaphylaxis Research
S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis | Litcius