Quercetin inhibits the NOX2/ROS-mediated NF-κB/TXNIP signaling pathway to ameliorate pyroptosis of cardiomyocytes to relieve sepsis-induced cardiomyopathy
Hao Zhao, Xin Lin, Qingfeng Chen, Xiaoyue Wang, Yongya Wu, Zhao Xiaoxia
Topics & Concepts
PyroptosisTXNIPDiabetic cardiomyopathyDownregulation and upregulationProgrammed cell deathNF-κBApoptosisPharmacologyCell biologyCancer researchMitochondrial ROSSignal transductionChemistryMedicineBiologyCardiomyopathyOxidative stressInternal medicineBiochemistryHeart failureGeneThioredoxinInflammasome and immune disordersNeutrophil, Myeloperoxidase and Oxidative MechanismsMitochondrial Function and Pathology