Pd(<scp>ii</scp>)-Catalyzed oxidative alkenylation of 4-hydroxycoumarin with maleimide <i>via</i> a C–H bond activation strategy
Kumud Sharma, Kashmiri Neog, Abhilash Sharma, Pranjal Gogoi
Abstract
A Pd(ii)-catalyzed oxidative alkenylation of 4-hydroxycoumarins with maleimides for the synthesis of 4-hydroxy-3-maleimidecoumarins has been described. This methodology proceeds via C-H activation and C(sp2)-C(sp2) bond formation providing a series of alkenylated Heck-type products.
Topics & Concepts
MaleimideChemistryOxidative phosphorylationCatalysisCombinatorial chemistryPolymer chemistryOrganic chemistryBiochemistryCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques