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Alcohol Etherification via Alkoxy Radicals Generated by Visible-Light Photoredox Catalysis

Alexandra R. Rivero, Peter Fodran, Alica Ondrejková, Carl‐Johan Wallentin

2020Organic Letters33 citationsDOIOpen Access PDF

Abstract

)-H bonds. This visible-light photoredox catalysis produces alkyl ethers via 1,5/6-hydrogen atom transfer or aryl ethers via 1,5-addition. This mild methodology provides a practical strategy for the synthesis of acetals, orthoesters, tetrahydrofurans, and chromanes.

Topics & Concepts

Photoredox catalysisChemistryHypervalent moleculeRadicalAlkoxy groupCatalysisReagentAlkylPhotochemistryArylAlcoholVisible spectrumCombinatorial chemistryHydrogen atomOrganic chemistryPhotocatalysisPhysicsOptoelectronicsRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods
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