Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial
Xiaofei Zhu, Yangsen Cao, Wenyu Liu, Xiaoping Ju, Xianzhi Zhao, Lingong Jiang, Yusheng Ye, Gang Jin, Huojun Zhang
Topics & Concepts
MedicinePembrolizumabGemcitabineTrametinibRadiation therapyOncologyRadiologyPancreatic cancerInternal medicineDeoxycytidinePhases of clinical researchClinical trialRadiosurgeryRadiomicsSurgical resectionChemoradiotherapyPancreatic neuroendocrine tumorImage-guided radiation therapySurgeryImmunotherapyExternal beam radiotherapyClinical endpointPancreatic and Hepatic Oncology ResearchCancer Immunotherapy and BiomarkersCancer Research and Treatments