Synthesis, in vitro antimicrobial assessment, and computational investigation of pharmacokinetic and bioactivity properties of novel trifluoromethylated compounds using in silico ADME and toxicity prediction tools
Siwar Ghannay, Adel Kadri, Kaïss Aouadi
Topics & Concepts
ADMEChemistryLipophilicityPharmacologyPharmacokineticsIn silicoIn vivoQuantitative structure–activity relationshipCombinatorial chemistryIn vitroBiochemistryStereochemistryMedicineBiologyGeneBiotechnologySynthesis and Catalytic ReactionsClick Chemistry and ApplicationsFluorine in Organic Chemistry