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Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells

Reziyamu Wufuer, Keli Liu, Jing Feng, Meng Wang, Shaofan Hu, Feilong Chen, Shanshan Lin, Yiguo Zhang

2024Free Radical Biology and Medicine11 citationsDOI

Topics & Concepts

NRF1CisplatinTranscription factorTranscriptomeDNA damageOlaparibChemistryCell biologyCancer cellBiologyCancer researchDNA repairPharmacologyGeneGene expressionDNABiochemistryCancerPoly ADP ribose polymeraseGeneticsChemotherapyPolymeraseGenomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsChemotherapy-induced organ toxicity mitigation
Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells | Litcius