Biocatalysis: Enzymatic Synthesis for Industrial Applications
Shuke Wu, Radka Šnajdrová, Jeffrey C. Moore, Kai Baldenius, Uwe T. Bornscheuer
Abstract
Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for pharmaceuticals as well for the flavors and fragrance industry, are the most prominent examples. In addition, biocatalysts are used on a large scale to make specialty and even bulk chemicals. This review intends to give illustrative examples in this field with a special focus on scalable chemical production using enzymes. It also discusses the opportunities and limitations of enzymatic syntheses using distinct examples and provides an outlook on emerging enzyme classes.
Topics & Concepts
BiocatalysisBiochemical engineeringSpeciality chemicalsOrganic synthesisScalabilityScale (ratio)Fine chemicalChemistryNanotechnologyCatalysisComputer scienceManagement scienceOrganic chemistryEngineeringMaterials scienceIonic liquidPhysicsQuantum mechanicsDatabaseEnzyme Catalysis and ImmobilizationMicrobial Metabolic Engineering and BioproductionBiofuel production and bioconversion