Spesolimab in patients with flare of generalized pustular psoriasis: A multicentre case‐series
Francesco Bellinato, Paolo Gisondi, Annunziata Dattola, Antonio Giovanni Richetta, Antonio Costanzo, Mario Valenti, Clara De Simone, Angelo Valerio Marzano, Martina Zussino, Elena Pezzolo, Massimo Nacca, Giovanni Pellacani, Giampiero Girolomoni
Abstract
F I G U R E 1 Reduction of disease severity assessed through Generalized Pustular Psoriasis PASI (GPPASI) (a) and Dermatology Life Quality Index (DLQI) (b) after 1 and 4 weeks of treatment with spesolimab 900 mg iv.Erythematous plaques covered by pustules/desquamation of the trunk and left arm in a 52-year-old woman of Moroccan origin, with a flare of GPP at baseline (c) and 8 days after the intravenous infusion of spesolimab 900 mg (d), showing a complete clinical remission (GPPASI score of 0).
Topics & Concepts
VenereologyMedicineDermatologyPsoriasisPsoriasis: Treatment and PathogenesisAutoimmune Bullous Skin DiseasesDrug-Induced Adverse Reactions