Sirt3-dependent regulation of mitochondrial oxidative stress and apoptosis contributes to the dysfunction of pancreatic islets after severe burns
Xinzhu Liu, Xiaoye Xie, Dawei Li, Zhaoxing Liu, Bohan Zhang, Yu Zang, Huageng Yuan, Chuanan Shen
Topics & Concepts
SIRT3Oxidative stressIsletEndocrinologyReactive oxygen speciesMitochondrionApoptosisInternal medicineBiologyMitochondrial ROSPancreatic isletsOxidative phosphorylationCell biologyGene knockdownChemistryInsulinAcetylationMedicineSirtuinBiochemistryGeneSirtuins and Resveratrol in MedicineBurn Injury Management and OutcomesPancreatic function and diabetes