A robust high-performance thin-layer chromatography method for the simultaneous estimation of chlorthalidone and metoprolol succinate using quality risk assessment and design of experiments-based enhanced analytical quality by design approach
Pintu Prajapati, Maria Patel, Shailesh Shah
Topics & Concepts
Quality by DesignHigh performance thin layer chromatographyCentral composite designResponse surface methodologyChlorthalidoneCritical quality attributesChromatographyComputer scienceMaterials scienceThin-layer chromatographyChemistryEngineeringOperations managementMedicineDiureticDownstream (manufacturing)EndocrinologyAnalytical Methods in PharmaceuticalsAnalytical Chemistry and ChromatographyPesticide Residue Analysis and Safety