Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF Inhibitor‒Resistant Melanoma
Chao Zhang, Inna Smalley, Michael F. Emmons, Ritin Sharma, Victoria Izumi, Jane L. Messina, John M. Koomen, Elena B. Pasquale, Peter Forsyth, Keiran S.M. Smalley
Topics & Concepts
MelanomaCancer researchCDC42Epithelial–mesenchymal transitionMAPK/ERK pathwayBiologyEPH receptor A2Histone deacetylase inhibitorHistone deacetylaseEndothelial stem cellSignal transductionMetastasisCell biologyCancerReceptor tyrosine kinaseHistoneBiochemistryGeneticsIn vitroGeneAxon Guidance and Neuronal SignalingHippo pathway signaling and YAP/TAZMelanoma and MAPK Pathways