Ferroptosis: the Good, the Bad and the Ugly

Abstract

Polyunsaturated ether phospholipids, previously thought to oppose propagation of lipid peroxidation, have been reported to promote the cells' susceptibility to ferroptotic cell death. A recent study by Zou and colleagues now sheds a new light on the importance of the peroxisome-ether phospholipid axis in modulating ferroptosis susceptibility and evasion.

Topics & Concepts