Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity
Lei Tian, Bo Xu, Yuqing Chen, Zhenlong Li, Jing Wang, Jianying Zhang, Rui Ma, Shuai Cao, Weidong Hu, E. Antonio Chiocca, Balveen Kaur, Michael A. Caligiuri, Jianhua Yu
Topics & Concepts
Oncolytic virusCCL5CetuximabCancer researchTumor microenvironmentChemokineBiologyImmune systemEpidermal growth factor receptorImmunologyCancerAntibodyT cellTumor cellsMonoclonal antibodyIL-2 receptorGeneticsVirus-based gene therapy researchCAR-T cell therapy researchViral Infectious Diseases and Gene Expression in Insects