An open-source application for the standardized burst identification from the integrated muscle sympathetic neurogram
Glen E. Foster, Brooke M. Shafer, Conan L. H. Shing
Abstract
The basic analysis of muscle sympathetic nerve activity (MSNA) requires the identification of pulse-synchronous bursts from the integrated neurogram before standard MSNA metrics can be quantified. This process is a time-consuming task requiring an experienced microneurographer to visually identify and manually label bursts. We developed an open-source, cross-platform application permitting a standardized approach for sympathetic burst identification and present the performance of this application against a manual scorer under basal conditions and during sympathoexcitatory stresses.
Topics & Concepts
MicroneurographyIsometric exerciseIntraclass correlationLatency (audio)MedicinePhysical medicine and rehabilitationReproducibilityComputer scienceHeart rateBlood pressureInternal medicineMathematicsBaroreflexStatisticsTelecommunicationsHeart Rate Variability and Autonomic ControlCardiovascular and exercise physiologyHigh Altitude and Hypoxia