Glycolytic regulatory enzyme PFKFB3 as a prognostic and tumor microenvironment biomarker in human cancers
Qingen Da, Lei Huang, Can Huang, Ze’e Chen, Zhitong Jiang, Fang Huang, Tao Shen, Lu Sun, Zilong Yan, Xiaoqiang Ye, Jing Yi, Yu Huang, Jingjing Da, Mingming Ren, Jikui Liu, Tao Wang, Zhen Han, Kunfu Ouyang
Abstract
as a clinical risk factor, which has a good predictive ability. Our study indicated that PFKFB3 is a potent regulatory factor for TME and has the potential to be a valuable prognostic biomarker in human tumor therapy.
Topics & Concepts
FangGlycolysisBiomarkerEnzymeTumor microenvironmentCancerCancer researchBiologyMedicineBiochemistryTumor cellsInternal medicineEcologyCancer, Hypoxia, and MetabolismFerroptosis and cancer prognosisEpigenetics and DNA Methylation