The integrated stress response as a key pathway downstream of mitochondrial dysfunction
Maria Bilen, Sara Benhammouda, Ruth S. Slack, Marc Germain
Topics & Concepts
MitochondrionCell biologyBiologyTranscription factorBiogenesisMitochondrial biogenesisProgrammed cell deathIntegrated stress responseOrganelleUnfolded protein responseAutophagyDNAJA3ATF4Cellular stress responseCellmitochondrial fusionApoptosisTranslation (biology)Fight-or-flight responseMitochondrial DNAGeneticsEndoplasmic reticulumMessenger RNAGeneMitochondrial Function and PathologyEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and Therapy