Editorial: The Role of Natural Products in Chronic Inflammation
Wenjun Deng, Hongzhi Du, Dahui Liu, Zhaocheng Ma
Abstract
Inflammation including acute and chronic inflammation is the body's defense response to external stimuli, such as pathogens, irritants, or infections. Inflammation is usually beneficial to the body. However, repeated stimulation of harmful substances or ineffective regulation of acute inflammation can lead to chronic inflammation Persistent inflammatory responses may lead to chronic inflammation-related diseases such as cardiovascular, neurodegenerative, and inflammatory bowel disease In addition, chronic inflammation is also involved in the physiological and pathological processes of various diseases, such as atherosclerosis (AS), rheumatoid arthritis (RA), depression, obesity, gout, Alzheimer's disease, and cancer Currently, steroidal and non-steroidal anti-inflammatory drugs (NSAIDs) with antiinflammatory, analgesic and other curative effects, are the most commonly used classical treatments for inflammation in clinical practice. However, long-term use of these drugs can cause kinds of adverse reactions While rational drug use, drugs with higher safety should be used as much as possible. Therefore, finding natural plant compounds without toxic side effects and good curative effects to replace traditional anti-inflammatory drugs is an urgent issue to be solved in the clinical treatment of inflammation-related diseases.