<i>Sophora interrupta</i>Bedd. root-derived flavonoids as prominent antiviral agents against Newcastle disease virus
Cherukupalle Bhuvaneswar, Aluru Rammohan, Baki Vijaya Bhaskar, Pappithi Ramesh Babu, Naveen Gujjar, Duvvuru Gunasekar, Madhuri Subbiah, Pallu Reddanna, Wudayagiri Rajendra
Abstract
The two flavonoids, maackiain and echinoisoflavanone from roots of<italic>Sophora interrupta</italic>Bedd. have shown prominent<italic>in vitro</italic>antiviral activities by preventing viral replication and transcription than Ribavirin against NDV in DF-1 cells.
Topics & Concepts
SophoraTraditional medicineNewcastle diseaseBiologySophora flavescensVirologyBotanyVirusMedicineTraditional Chinese medicineNeuroscienceAlternative medicinePathologyMatrineBioactive natural compoundsSynthesis and biological activityComputational Drug Discovery Methods