Peptide–MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs)
Yanan He, Pragati Agnihotri, Sneha Rangarajan, Yi-Hong Chen, Melissa C. Kerzic, Buyong Ma, Ruth Nussinov, Roy A. Mariuzza, John Orban
Topics & Concepts
T-cell receptorAllosteric regulationMajor histocompatibility complexMHC class IIBiologyMHC class IT cellCD3MHC restrictionCell biologyReceptorCD8Immune systemBiochemistryGeneticsT-cell and B-cell ImmunologyImmune Cell Function and InteractionMonoclonal and Polyclonal Antibodies Research