Endometrial organoids: a reservoir of functional mitochondria for uterine repair
Sunyoung Hwang, Danbi Lee, Gaeun Lee, Jungho Ahn, Yu‐Gyeong Lee, Hwa Seon Koo, Youn‐Jung Kang
Abstract
Our findings suggest that endometrial organoid-originating mitochondria might be key players to mediate uterine repair resulting in fertility enhancement by recovering abrogated metabolic circumstance of the endometrium with AS. Further studies addressing the clinical applicability of endometrial organoids may aid in identifying new therapeutic strategies for infertility in patients with AS.
Topics & Concepts
OrganoidEndometriumTransplantationBiologyInfertilityUterusAndrologyPathologyMedicineInternal medicineCell biologyEndocrinologyPregnancyGeneticsEndometriosis Research and TreatmentReproductive System and PregnancyUterine Myomas and Treatments