Impact of tumor heterogeneity and microenvironment in identifying neoantigens in a patient with ovarian cancer
Tao Dao, Martin G. Klatt, Tatyana Korontsvit, Sung Soo Mun, Sean Guzman, Marissa S. Mattar, Oliver Zivanovic, Chrisann Kyi, Nicholas D. Socci, Roisin E. O’Cearbhaill, David A. Scheinberg
Topics & Concepts
Ovarian cancerEpitopeHuman leukocyte antigenBiologyCancer researchExomeTumor microenvironmentMajor histocompatibility complexImmunotherapyOvarian tumorAntigenCancerImmunologyExome sequencingImmune systemMutationGeneGeneticsImmunotherapy and Immune ResponsesImmune Cell Function and InteractionCancer Immunotherapy and Biomarkers