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Invited Commentary: Is Bias Towards the Null From Nondifferential Misclassification Wishful Thinking?

Ghassan B. Hamra

2022American Journal of Epidemiology12 citationsDOI

Abstract

In their article, Yland et al. (Am J Epidemiol. 2022;191(8):1485-1495) bring renewed attention to the oft-cited heuristic "nondifferential misclassification biases results towards the null." They make a compelling case, as others have before, that this heuristic is misguided. Herein, I briefly discuss the history of this heuristic, discuss why I believe it became and stayed popular, and note the very limited circumstances for which it may be appropriate.

Topics & Concepts

Wishful thinkingNull (SQL)MedicinePsychologyCognitive psychologyComputer scienceData miningHealthcare cost, quality, practicesForecasting Techniques and ApplicationsHealth Systems, Economic Evaluations, Quality of Life
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