Litcius/Paper detail

Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression

Daniel M. Sapozhnikov, Moshe Szyf

2022Nature Protocols18 citationsDOI

Topics & Concepts

DNA demethylationBiologyDNA methylationCRISPREpigeneticsDNAGeneticsTranscription (linguistics)MethylationGeneMolecular biologyGene expressionLinguisticsPhilosophyCRISPR and Genetic EngineeringEpigenetics and DNA MethylationPluripotent Stem Cells Research
Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression | Litcius