Ultraviolet-induced photodegradation elevated the toxicity of polystyrene nanoplastics on human lung epithelial A549 cells
Qingying Shi, Jingchun Tang, Xiaomei Liu, Rutao Liu
Abstract
UV-induced photodegradation posed greater cytotoxicity, as clearly evidenced by the impaired cell viability, stronger oxidative stress, serious membrane damage, intensive mitochondrial dysfunction, and the altered transcriptome responses.
Topics & Concepts
PhotodegradationOxidative stressCytotoxicityToxicityViability assayA549 cellUltravioletHuman lungChemistryCell biologyTranscriptomeReactive oxygen speciesCellLungBiologyIn vitroMaterials scienceMedicineBiochemistryGeneInternal medicineGene expressionOrganic chemistryOptoelectronicsPhotocatalysisCatalysisMicroplastics and Plastic PollutionNanoparticles: synthesis and applicationsGraphene and Nanomaterials Applications