Identification of novel benzothiopyranones with ester and amide motifs derived from active metabolite as promising leads against Mycobacterium tuberculosis
Peng Li, Bin Wang, Lei Fu, Kaijing Guo, Chen Ma, Baolian Wang, Ziyun Lin, Gang Li, Haihong Huang, Yu Lu
Topics & Concepts
DruggabilityChemistryMycobacterium tuberculosisMetaboliteAntimycobacterialTuberculosisIn vitroAmideCytotoxicityStereochemistrySmall moleculeActive metaboliteBiochemistryMedicinePathologyGeneTuberculosis Research and EpidemiologyCancer therapeutics and mechanismsSynthesis and biological activity