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Identification of novel benzothiopyranones with ester and amide motifs derived from active metabolite as promising leads against Mycobacterium tuberculosis

Peng Li, Bin Wang, Lei Fu, Kaijing Guo, Chen Ma, Baolian Wang, Ziyun Lin, Gang Li, Haihong Huang, Yu Lu

2021European Journal of Medicinal Chemistry12 citationsDOI

Topics & Concepts

DruggabilityChemistryMycobacterium tuberculosisMetaboliteAntimycobacterialTuberculosisIn vitroAmideCytotoxicityStereochemistrySmall moleculeActive metaboliteBiochemistryMedicinePathologyGeneTuberculosis Research and EpidemiologyCancer therapeutics and mechanismsSynthesis and biological activity
Identification of novel benzothiopyranones with ester and amide motifs derived from active metabolite as promising leads against Mycobacterium tuberculosis | Litcius