Integrated NLRP3, AIM2, NLRC4, Pyrin inflammasome activation and assembly drive PANoptosis
SuHyeon Oh, Jihye Lee, Ju-Eun Oh, G. Yu, Haesun Ryu, Daesik Kim, SangJoon Lee
Topics & Concepts
InflammasomeAIM2Multiprotein complexPyrin domainNLRC4Innate immune systemCell biologyBiologyCaspase 1Signal transducing adaptor proteinPattern recognition receptorInflammationSignal transductionImmunologyImmune systemBiochemistryGeneInflammasome and immune disordersinterferon and immune responsesHeme Oxygenase-1 and Carbon Monoxide