Three-component heteroannulation for tetrasubstituted furan construction enabled by successive defluorination and dual sulfonylation relay
Song‐Zhou Cai, Danhua Ge, Li-Wen Sun, Weidong Rao, Xin Wang, Zhi‐Liang Shen, Xue‐Qiang Chu
Abstract
An efficient method for the facile assembly of fluoroalkylated tetrasubstituted furan derivatives <italic>via</italic> a three-component cascade reaction of polyfluoroalkyl peroxide with sulfinates was developed.
Topics & Concepts
FuranComponent (thermodynamics)ChemistryDual (grammatical number)Combinatorial chemistryPeroxideCascadeRelayOrganic chemistryChromatographyPower (physics)PhysicsLiteratureArtThermodynamicsQuantum mechanicsSulfur-Based Synthesis TechniquesFluorine in Organic ChemistryCyclopropane Reaction Mechanisms