Supercritical antisolvent-fluidized bed for the preparation of dry powder inhaler for pulmonary delivery of nanomedicine
Zhimin Ma, Xuejuan Zhang, Lu Ping, Zicheng Zhong, Xiubing Zhang, Xiaodong Zhuang, Guanlin Wang, Qiupin Guo, Shaofeng Zhan, Zhenwen Qiu, Ziyu Zhao, Qingguo Li, Dandong Luo
Topics & Concepts
Dry-powder inhalerSupercritical fluidDissolutionNanomedicineFluidized bedParticle sizeActive ingredientMaterials scienceInhalerChromatographyNanoparticleMicronizationSpray dryingDrug deliveryAerosolizationGranulationDissolution testingChemical engineeringNanotechnologyChemistryInhalationPharmacologyMedicineComposite materialOrganic chemistryAsthmaEngineeringAnatomyBiopharmaceutics Classification SystemInternal medicineInhalation and Respiratory Drug DeliveryMicroencapsulation and Drying ProcessesPhase Equilibria and Thermodynamics