wSDTNBI: a novel network-based inference method for virtual screening
Zengrui Wu, Hui Ma, Zehui Liu, Lulu Zheng, Zhuohang Yu, Shuying Cao, Wenqing Fang, Lili Wu, Weihua Li, Guixia Liu, Jin Huang, Yun Tang
Abstract
experiments demonstrated that ursonic acid and oleanonic acid have therapeutic effects on multiple sclerosis. These results indicate that wSDTNBI might be a powerful tool for network-based VS in drug discovery.
Topics & Concepts
InferenceNatDrug discoveryVirtual screeningComputational biologyComputer scienceData miningArtificial intelligenceBioinformaticsBiologyComputer networkComputational Drug Discovery MethodsReceptor Mechanisms and SignalingRetinoids in leukemia and cellular processes