Litcius/Paper detail

BCMA biology and therapeutic targeting in multiple myeloma: From ligand signaling to antigen escape

Ebru Sezer, Seungyoun Lee, Junho Chung

2025Seminars in Hematology7 citationsDOI

Topics & Concepts

Chimeric antigen receptorAntigenBiologyComputational biologyContext (archaeology)Signal transductionCell biologyReceptorFunction (biology)Plasma cellMultiple myelomaCancer researchSystems biologyHEK 293 cellsExtracellularGeneImmunologyBispecific antibodyChemical biologyGeneticsPlasma protein bindingSmall hairpin RNACell signalingT cellMutationMissense mutationSynthetic biologyTranscriptomeLigand (biochemistry)Cell growthGain of functionBioinformaticsMultiple Myeloma Research and TreatmentsCAR-T cell therapy researchProtein Degradation and Inhibitors