Litcius/Paper detail

A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function

Ciaran P. A. Doherty, Sabine M. Ulamec, Roberto Maya‐Martinez, Sarah C. Good, Jemma Makepeace, G. Nasir Khan, Patricija van Oosten‐Hawle, Sheena E. Radford, David J. Brockwell

2020Nature Structural & Molecular Biology212 citationsDOIOpen Access PDF

Topics & Concepts

Protein aggregationChemistryIn vitroSequence (biology)Sequence motifBiochemistryBiophysicsBiologyCell biologyGeneAlzheimer's disease research and treatmentsParkinson's Disease Mechanisms and TreatmentsCholinesterase and Neurodegenerative Diseases