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Computational Modeling and Pharmacokinetics/ADMET Study of Some Arylpiperazine Derivatives as Novel Antipsychotic Agents Targeting Depression

Sabitu Babatunde Olasupo, Adamu Uzairu, Gideon Shallangwa Adamu, Sani Uba

2020Chemistry Africa23 citationsDOI

Topics & Concepts

Quantitative structure–activity relationshipIn silicoPharmacophorePharmacokineticsChemistryhERGSerotonin transporterPharmacologyAntipsychoticComputational biologyStereochemistryBiochemistryReceptorMedicineBiologyGeneSerotoninSchizophrenia (object-oriented programming)Internal medicinePotassium channelPsychiatryComputational Drug Discovery MethodsTreatment of Major DepressionSynthesis and biological activity
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