Protein detection in blood with single-molecule imaging
Chih‐Ping Mao, Shih-Chin Wang, Yu‐Ping Su, Ssu-Hsueh Tseng, Liangmei He, Annie A. Wu, Richard B.S. Roden, Jie Xiao, Chien‐Fu Hung
Abstract
M) range. We demonstrate SMAC in a variety of applications with human blood samples, including the analysis of disease-associated secreted proteins, membrane proteins, and rare intracellular proteins. SMAC opens the door to the application of single-molecule imaging in noninvasive disease profiling.
Topics & Concepts
ChemistryComputational biologyBiophysicsBiologyAdvanced Biosensing Techniques and ApplicationsAdvanced Fluorescence Microscopy TechniquesMonoclonal and Polyclonal Antibodies Research