Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors
Gregory T. Motz, Stephen P. Santoro, Liping Wang, Tom Garrabrant, Ricardo R. Lastra, Ian S. Hagemann, Priti Lal, Michael D. Feldman, Fabián Benencia, George Coukos
Topics & Concepts
Fas ligandCancer researchImmune systemCD8FOXP3BiologyTumor microenvironmentImmunologyParacrine signallingCytotoxic T cellCell biologyApoptosisProgrammed cell deathReceptorIn vitroBiochemistryAngiogenesis and VEGF in CancerCancer Immunotherapy and BiomarkersT-cell and B-cell Immunology