Immune-Complex Glomerulonephritis After COVID-19 Infection
Sanjeev Sethi, Matthew R. D’Costa, Sandra M. Hermann, Samih H. Nasr, Fernando C. Fervenza
Abstract
Acute kidney injury is frequently present in severe acute respiratory syndrome coronavirus 2 infection (coronavirus disease 2019 [COVID-19]).1 In addition, many patients positive for COVID-19 also develop proteinuria and collapsing glomerulopathy.2-4 We recently encountered a kidney biopsy specimen showing an immune complex-glomerulonephritis (GN) after a recent COVID-19 infection. To the best of our knowledge, an immune-complex GN has not been described in the setting of COVID-19 infection.
Topics & Concepts
MedicineGlomerulopathyImmune systemCoronavirus disease 2019 (COVID-19)GlomerulonephritisProteinuriaImmunologyImmune complex diseaseImmune complexRenal biopsyCoronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Acute kidney injury2019-20 coronavirus outbreakKidneyBiopsyDiseasePathologyInfectious disease (medical specialty)Internal medicineOutbreakCOVID-19 Clinical Research StudiesRenal Diseases and GlomerulopathiesPancreatitis Pathology and Treatment