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Variables predicting clinical remission among adults with severe asthma treated with biologic agents

Selma Yeşilkaya, Kurtuluş Aksu, Gürgün Tuğçe Vural Solak, Özgür Akkale, Onur Telli, Hatice Çelik Tuğlu, Gözde Köycü Buhari, Sakine Nazik Bahçecioğlu, Sezgin Demir

2023European Annals of Allergy and Clinical Immunology11 citationsDOIOpen Access PDF

Abstract

Background: Although biologic agents promise a short-to medium-term remission in asthma, it is unclear whether they can fundamentally alter disease course and achieve long-term remission. We aimed to investigate the clinical remission success of biologics in patients with severe asthma and the factors associated with remission.

Topics & Concepts

MedicineAsthmaMepolizumabInternal medicineUnivariate analysisLogistic regressionOmalizumabGastroenterologyPediatricsMultivariate analysisImmunoglobulin EImmunologyEosinophilAntibodyAsthma and respiratory diseasesRespiratory and Cough-Related ResearchIL-33, ST2, and ILC Pathways