Adaptive evolution of West Nile virus facilitated increased transmissibility and prevalence in New York State
Sean Bialosuknia, Alan P. Dupuis, Steven D. Zink, Cheri A. Koetzner, Joseph G. Maffei, Jennifer C. Owen, Hannah Landwerlen, Laura D. Kramer, Alexander T. Ciota
Abstract
) was additionally completed to assess viremia kinetics of NY10 relative to WN02. Modelling the increased infectivity and transmissibility of the NY10 strains together with strain-specific viremia demonstrates a mechanistic basis for selection that has likely contributed to the increased prevalence of WNV in NYS.
Topics & Concepts
Transmissibility (structural dynamics)West Nile virusVirologyBiologyVirusPhysicsVibration isolationQuantum mechanicsVibrationMosquito-borne diseases and controlViral Infections and VectorsCOVID-19 epidemiological studies