Knockout of the C3a receptor protects against renal ischemia reperfusion injury by reduction of NETs formation
Xiaoting Wu, Danyu You, Maoen Pan, Mengjie Weng, Qionghong Xie, Yi Guan, Jing Zheng, Songhua Lin, Xiaohong Zhang, Chuan‐Ming Hao, Jianxin Wan
Topics & Concepts
Neutrophil extracellular trapsAcute kidney injuryInflammationOxidative stressKidneyPharmacologyRenal ischemiaReperfusion injuryIschemiaReactive oxygen speciesComplement systemInnate immune systemKnockout mouseBlockadeReceptorMedicineImmunologyBiologyCell biologyImmune systemInternal medicineNeutrophil, Myeloperoxidase and Oxidative MechanismsAcute Kidney Injury ResearchVasculitis and related conditions