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Deep learning-based decision support system for the diagnosis of neoplastic gallbladder polyps on ultrasonography: Preliminary results

Younbeom Jeong, Jung Hoon Kim, Hee‐Dong Chae, Sae‐Jin Park, Jae Seok Bae, Ijin Joo, Joon Koo Han

2020Scientific Reports50 citationsDOIOpen Access PDF

Abstract

Ultrasonography (US) has been considered image of choice for gallbladder (GB) polyp, however, it had limitations in differentiating between nonneoplastic polyps and neoplastic polyps. We developed and investigated the usefulness of a deep learning-based decision support system (DL-DSS) for the differential diagnosis of GB polyps on US. We retrospectively collected 535 patients, and they were divided into the development dataset (n = 437) and test dataset (n = 98). The binary classification convolutional neural network model was developed by transfer learning. Using the test dataset, three radiologists with different experience levels retrospectively graded the possibility of a neoplastic polyp using a 5-point confidence scale. The reviewers were requested to re-evaluate their grades using the DL-DSS assistant. The areas under the curve (AUCs) of three reviewers were 0.94, 0.78, and 0.87. The DL-DSS alone showed an AUC of 0.92. With the DL-DSS assistant, the AUCs of the reviewer's improved to 0.95, 0.91, and 0.91. Also, the specificity of the reviewers was improved (65.1-85.7 to 71.4-93.7). The intraclass correlation coefficient (ICC) improved from 0.87 to 0.93. In conclusion, DL-DSS could be used as an assistant tool to decrease the gap between reviewers and to reduce the false positive rate.

Topics & Concepts

MedicineIntraclass correlationGallbladderConvolutional neural networkUltrasonographyRadiologyBinary classificationArtificial intelligenceDifferential diagnosisInternal medicinePathologySupport vector machineComputer sciencePsychometricsClinical psychologyCholangiocarcinoma and Gallbladder Cancer StudiesRadiomics and Machine Learning in Medical Imaging
Deep learning-based decision support system for the diagnosis of neoplastic gallbladder polyps on ultrasonography: Preliminary results | Litcius