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Electrochemical Detection of Synthetic Vanillin Using a Strontium Pyrophosphate Nanorod-Modified Electrode

Balasubramanian Sriram, Sakthivel Kogularasu, Sea‐Fue Wang, Guo‐Ping Chang‐Chien

2025ACS Materials Au24 citationsDOIOpen Access PDF

Abstract

High Resolution Image Download MS PowerPoint Slide Synthetic vanillin (VLN) is extensively utilized as a flavoring agent in the food and pharmaceutical industries, raising health concerns due to its synthetic origin and widespread consumption. Strontium phosphate (Sr 2 P 2 O 7 ) has been a desirable electrode modifier in recent years due to its distinct structural and electrochemical characteristics. Due to its stability, efficacy, and electrocatalytic capabilities, Sr 2 P 2 O 7 has emerged as a competent electrocatalytic material. This study presents the fabrication and application of a screen-printed carbon electrode (SPCE) modified with Sr 2 P 2 O 7 nanorods as a sensitive and selective electrochemical sensor for VLN detection. Sr 2 P 2 O 7 nanorods were synthesized via a sonochemical approach and thoroughly characterized by spectroscopic and electrochemical techniques to confirm their structural and functional properties. Quantification of VLN was achieved using a sensitive amperometric ( i – t ) technique, yielding a lower detection limit of 0.52 nM and a wide linear detection range of 0.001–726.8 μM. Additionally, real-sample analyses in food samples exhibited recovery rates (±98.00–99.66%), underscoring the platform’s practical applicability for monitoring synthetic VLN in real-world conditions. This work highlights the potential of Sr 2 P 2 O 7 -modified SPCEs as reliable tools for food safety applications, offering a cost-effective, disposable solution for synthetic vanillin detection.

Topics & Concepts

StrontiumPyrophosphateNanorodElectrodeVanillinElectrochemistryMaterials scienceNanotechnologyChemistryOrganic chemistryEnzymePhysical chemistryBiochemical and biochemical processesElectrochemical sensors and biosensorsAdvanced Chemical Sensor Technologies